August 13, 2010

A Curious Look At The 3.39 Million Year Old “Stone Tool Markings” From Dikika, Ethiopia

I don’t know who this is worse for, the editors & reviewers over at Nature or the authors of the article who can’t tell the difference between crocodile teeth markings and stone tool modification, nor raise the possibility. The paper, “Evidence for stone-tool-assisted consumption of animal tissues before 3.39 million years ago at Dikika, Ethiopia,” very confidently proclaims unambiguous evidence for,

“stone-tool-inflicted marks on bones found during recent survey work in Dikika, Ethiopia, a research area close to Gona and Bouri. On the basis of low-power microscopic and environmental scanning electron microscope observations, these bones show unambiguous stone-tool cut marks for flesh removal and percussion marks for marrow access.”

Butchered by early humans or eaten by crocodiles? Image: David DeGusta

Given that the said rib fragment, DIK-55-2, came from a prehistoric lacustrine site. These markings could have been produced by crocodiles. Crocs, if you aren’t aware of (ahem editors and publishing group) are very abundant in the Rift Valley — both currently and prehistorically. On top of that, crocs like to eat meat and scavenge. Yes its true, they are carnivores. Australopithecines were at most ominivores, with wide based teeth useful in grinding tubers and nuts. Crocs have more meat shearing, bone crushing teeth than 3.39 million year old stone tools, which there are none of at the moment.

Given that there really isn’t an archaeological record for Australopithecine tools, I’ll take a gander and say crocs like to eat meat and scavenge more effectively than A. afarensis could make and use said tools to butcher a large ungulate. They have been on this Earth for roughly 197 million years more than hominins have and they are really good at what they do… Again, probably better than a species of hominins who did not live in the Stone Age. It is just as likely (if not more) that the markings were produced by crocodiles just given the ecological context.

Now just how different at cut marks from crocodile teeth marks? David DeGusta, from Stanford University, compared and contrasted the two different markings using images from Njau and Blumenchine (2006) paper titled, “A diagnosis of crocodile feeding traces on larger mammal bone, with fossil examples from the Plio-Pleistocene Olduvai Basin, Tanzania,” to those published in the current Nature article. I’ve inserted DeGusta’s image into this post on right for your own inspection. DeGusta was also on Science Friday, discussing this possibility, with one of the article’s authors, Zeresenay Alemseged. What do you think? Do they look completely different or similar? Seriously, I am asking you to comment. I’d like to know what you see.

Personally I don’t see much of a difference. I agree that stone tools marks are more V shaped, while croc teeth are more pitted/rounded. But take this into light: tool use, especially butchery, is a very human behavioral trait. In their search to attribute this human behavior to a primitive hominin species who roamed 800,000 years earlier, to the era of Australopithecus afarensis, without considering another possible explanation, the authors and editors of Nature were somewhat foolish.

Many paleoanthropologists are in this mad rush to claim their precious find is the most human of hominins, so as to etch their name into the textbooks in rewriting human evolution, that they sometimes forget about doing thorough comparative science. And many publications are in this mad rush to publish the most human of findings, that they sometimes forget about thoroughly editing scientific works. Think that could be the case? I sure do… Why should we settle on secondary evidence for Australopithecine stone tools when none have been found yet, and when another possibility hasn’t been extensively exhausted?

    McPherron, S., Alemseged, Z., Marean, C., Wynn, J., Reed, D., Geraads, D., Bobe, R., & Béarat, H. (2010). Evidence for stone-tool-assisted consumption of animal tissues before 3.39 million years ago at Dikika, Ethiopia Nature, 466 (7308), 857-860 DOI: 10.1038/nature09248

August 12, 2010

Should Neandertals Be Recategorized As A Subspecies Of Humans?

Earlier this week, I saw a friend reading this article, and considering SciAm has proven to be a bastion of intellectual stimulation and unbiased discussion, I decided to share it with you. Since the publication of the Neandertal draft genome in May, the concept of reorganizing the human family tree to include Neandertals as a subspecies is not particularly new in the world of paleoanthropology. I wonder why, though, did SciAm decide to publish this discussion now?

Anyways, if you want a synopsis of the thesis of the article, read this excerpt:

“Thus it is—revealing the identity of my example—that we must reclassify Homo neanderthalensis as Homo sapiens neanderthalensis, a subspecies of Homo sapiens. A comprehensive and technically sophisticated study published in the May 7 issue of Science, “A Draft Sequence of the Neandertal Genome,” by Max Planck Institute evolutionary anthropologists Richard E. Green, Svante Pääbo and 54 of their colleagues, demonstrates that “between 1 and 4% of the ge nomes of people in Eurasia are derived from Neandertals” and that “Neandertals are on average closer to individuals in Eurasia than to individuals in Africa.” In fact, the authors note, “a striking observation is that Neandertals are as closely related to a Chinese and Papuan individual as to a French individual…. Thus, the gene flow between Neandertals and modern humans that we detect most likely occurred before the divergence of Europeans, East Asians, and Papuans.” In other words, our anatomically hirsute cousins are actually our genetic brothers.”

I did a real life facepalm when I came upon Shermer’s argument for including them as a subspecies,

“I always suspected that Neandertals and anatomically modern humans interbred, based on a simple observation: humans are the most sexual of all the primates, willing and able to do it just about anywhere, anytime, with anyone (and even with other species…).”

You have to be a paid subscriber to read the rest of article, so I can’t really know if he’s totally serious about his argument or not. Considering he goes on supporting his argument citing the book of human sexual behavior, the Kinsey Reports, I’m afraid that he actually is pretty confident his argument is legit. Sigh.

If this is true, this is a sad state of affairs for scientific publications; when reporters decide to serve up asinine explanations to scientific phenomenon. I am of the opinion that Shermer, nor any reporter, has the position to give reasons to why evolution occurred a certain way. Shermer could have spent his article discussing the differences between anatomy and material culture between the Neandertals and humans, and how the genetic lines of evidence, both mtDNA and nuclear DNA intersect and diverge from those.

He could have synthesized many different schools of thought on Neandertal ancestry and modern human evolution, but he chose to focus on something taboo. Sex certainly sells, I guess even for SciAm… But the thought that modern-ish humans reproduced with Neandertals is certainly not something unthinkable. So why focus on it?

June 16, 2010

Were The Americas Settled Twice?

A team of paleoanthropologists report in PLoS One analyzed the skulls of several dozen 11,000 year old Paleoamericans and compared them to the skulls of more than 300 1,000 year old Amerindians. They concluded that based on the morphology, there were two distinct waves of colonizers from Asia.

11,000 Year Old Lagoa Santa Brazil Paleoamerican Skull

11,000 Year Old Lagoa Santa Brazil Paleoamerican Skull

While we know from a couple genetic studies there are at least two, if not 3 or more waves of colonizers, the morphological evidence is now beginning to make a lot more sense along with the genetic evidence. There’s some concern why the authors didn’t have more North American and Asian samples for comparison, but that’s almost always a critique in any anatomical study.

Two comments in the Science Now news article are particularly entertaining regarding this topic:

“Very interesting–don’t tell some of the tribes in california–they won’t be able to handle real information like this.”

“Exactly. It sounds like the Amerindians stole the land from the Paleoindians? I guess they should pay restitution, right?”

    Hubbe, M., Neves, W., & Harvati, K. (2010). Testing Evolutionary and Dispersion Scenarios for the Settlement of the New World PLoS ONE, 5 (6) DOI: 10.1371/journal.pone.0011105

June 4, 2010

Early hominin ate “seafood”, possible reason for the expansion of the brain

Recent archaeological find in Koobi Fora, Kenya suggests that our early ancestors might have dined on “seafood” to compensate for the energy needed for the expansion of the brain. The excavated site dates 1.95 million years ago, which predates Homo erectus, reveals distinct faunal remains (some with evidence of butchery) and Oldowan artifacts. Detailed in latest PNAS edition, archaeologist David Braun and his team found an assemblage of bones from terrestrial and aquatic animals such as fishes, turtles and even crocodiles along with stone fragments (Oldowan tools) that are thought to be used to cut these animals with.

Photograph and scanning electron microscope image of a reptile bone scored by cuts. Image from PNAS.

“These aquatic foods are really important sources of the long-chain polyunsaturated fatty acids and docosahexaenoic acid that are so critical to human brain growth,” said co-author and paleoanthropologist Dr. Richmond. “Finding these foods in the diets of our early ancestors suggests they may have helped to lift constraints on brain size and fuel the evolution of a larger brain.”

Braun posits that if these early hominins indeed ate these terrestrial and aquatic animals (fishes, turtles and crocodiles), then they would have ingested enough calories and fatty acids needed for the expansion of the brain without having to scavenge for animal remains. Braun thinks that these small-bodied hominins would have avoided the dangerous risk of confronting with larger scavengers.

Read more:

Crocs and fish key to human evolution on PhysOrg.

Did Dining on Seafood Help Early Humans Grow These Big Brains? on Discover.

Fossils Suggest Menu That Made Humans Possible on Wired.

Early hominin diet included diverse terrestrial and aquatic animals 1.95 Ma in East Turkana, Kenya (Braun et al., 2010) on PNAS.

Originally posted on The Prancing Papio.

May 21, 2010

Another Homo in the family!

I just love saying, “Another Homo in the family”! Anyways, it seems like a new species of Homo has been identified from a partial skull found in Sterkfontein Caves, near Johannesburg by anthropologist Dr. Darren Curnoe from University of New South Wales (School of Biological, Earth and Environmental Sciences) and paleoanthropologist Dr. Phillip Tobias. This specimen, known only by its museum catalog name Stw 53, was  found in 1977 and had largely been ignored until Dr. Curnoe restored and reconstructed the skull with Dr. Tobias. They had initially concluded that Stw 53 is a Homo habilis but after years of examination and comparing it with other fossils, they are both confident that Stw 53 is a new species and named it Homo gautengensis.

Side by side comparison. Stw 53 (Homo gautengensis), (left) and KNM ER 1813 (Homo habilis), (right). H. gautengensis photo by Dr. Darren Curnoe and H. habilis photo from Wikipedia.

Dr. Curnoe believe that H. gautengensis predates H. habilis, making it the earliest Homo in our family tree so far. H. gautengensis walked upright in southern Africa about two million years ago until 600,000 years ago. Fully grown, it stood about 3 feet tall (just over 1 meter tall) and weigh about 110 lbs (about 50 kilograms). It has relatively large molars and premolars, which suggest that its diet consist large of plant matter and requires a lot of chewing. There were stone tools found near Stw 53, described as “fairly primitive” by Dr. Curnoe. They are also thought to have the knowledge of fire, perhaps using it to obtain and/or prepare food. Stw 53 was found in the same caves with Australopithecus africanus and Australopithecus robustus (or Paranthropus robustus). However, Dr. Curnoe does not believe that H. gautengensis gave rise to Homo sapiens.


Reference:

Beale B. 2010. New species of human ancestor identified. Retrieved May 21, 2010 http://www.science.unsw.edu.au/news/new-species-of-human/

Originally posted on The Prancing Papio.

May 16, 2010

Genetics of High Altitude Life

Almost every biological anthropology text-book I’ve ever looked at has described the adaptations of human populations to the environments they occupy. Examples they give are the short stalky Inuit adapted to conserving heat in cold environments, the long lanky East African nomads adapted to far distant travels, and the barrel chested Peruvian and Tibetans living in low oxygen environments.

Highland Tibet

Highland Tibet

Little discussion, beyond correlating ecology and physical observation, is given to these. Actually I lie, the physiology of the barrel chested high altitude occupants is given a couple of sentences as well as an elevated oxygen binding capacity without concentrating their blood.

A paper published in Science several days ago tackles this latter issue. A group of scientists looked for unique alleles among Tibet highlanders and discovered 10 unique oxygen-processing alleles. I don’t have full access to the publication, so can’t tell if these genes encode for completely different functioning proteins or are differentially regulated at high altitudes.

All I can derive is that these genes seem to prevent polycythemia, edematous swelling of the lungs and brain, and hypertension of the pulmonary vasculature, which are all complications of high altitude living.  Two of these genes are EGLN1 and PPARA. PPARA is a peroxisome proliferation proteins that also is a leukotriene antagonist. That is interesting because in obstructive conditions like asthama, leukotrienes induce vasospasm and bronchconstriction. EGLN1 is also has an interesting role,

“it is a protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis.”

These two genes were significantly associated with the decreased hemoglobin phenotype that is unique to this highland population.

    Simonson TS, Yang Y, Huff CD, Yun H, Qin G, Witherspoon DJ, Bai Z, Lorenzo FR, Xing J, Jorde LB, Prchal JT, & Ge R (2010). Genetic Evidence for High-Altitude Adaptation in Tibet. Science (New York, N.Y.) PMID: 20466884

May 6, 2010

The Neandertal Draft Genome

Every time big anthropology news has come out in the last year or so, I’m too busy and drowned under the sea of books and notes for my upcoming exams to immerse myself in it. This happened with Ardipithecus last fall, and now with the draft of the Neandertal genome coming out tomorrow, I can’t help but feel a bit left out. The complete mitochondrial Neandertal genome was released a little under 2 years ago… and now because of high throughput sequencing technology, the draft genome is now complete.

Currently, Science has put up a special section of their website dedicated to this. The news agencies are having issues with embargoes and what not, they put up articles and then take them down. But the word is out, Green and Pääbo’s project to sequence the Neandertal genome is out and there are some interesting findings:

  • The comparison of 3 Neandertal samples to 5 modern human genomes showed that Neandertal genome is closer to some populations of modern humans than others
  • About 10 loci had distinctly non-African hallmarks
  • There’s an attributable 1-4% Neandertal ancestry to non-African modern human populations

There’s a lot more behind this all than I really have time for, unfortunately. So be sure to check out Razib, John Hawks, etc. for all the goodies.

May 2, 2010

The Genetics of DCC, Netrin & Mirror Movements Discovered

From Nobel Intent comes news of a discovery in the Mendelian genetics of Mirror Movements, a condition that causes people to involuntarily move both sides of their body when they intended to only move one.

Aside from being medically relevant, interesting on a population genetics level, and involved an Iranian family, it also caught my eye because about 3 weeks ago we covered the implications of DCC (deleted in colon cancer gene, I know — very clever!) mutations in my pathology course. DCC mutations are found in the sequence of events that lead up to a special type of familial adenomatous polyposis (FAP), known as Gardner syndromes.  These colon cancers occurs primarily on the left or descending colon. The morphology of FAP cancers lead to a napkin ring like constriction of the colon that present as alternating bouts of diarrhea and constipation. What makes them unique from other FAPs is that they have present with extracolonic manifestation, like bone cancers.

The DCC gene is on the long arm of chromosome 18. I know that it is a cell surface protein responsible for cell-to-cell and cell-to-matrix adhesion. Normally when cells proliferate, they squeeze up on each other and DCC works via contact inhibition to signal a stop in proliferation because conditions are getting too cramped. Therefore, if DCC is deleted, contact inhibition is lost and cell loses ability to proliferate, yielding a dysplastic growth.

Genbank classifies this gene as one that encodes for a netrin 1 receptor, which I did not know before I read this post. I find this really interesting in the relevance of DCC to Mirror Movements. Dr. John Nicholls,of SISSA in Trieste, Italy,  the dude for neurodevelopment, guest lectured my neuroscience course during my second term of medical school last year. I remember him describing netrins as a class of axon guiding proteins that functioned during growth and development. The hallmark experiment I remember him citing was the Oster, et al., 2004, where ganglion cell axon pathfinding in the retina and optic nerve was guided by netrin signals.

It seems that in Mirror Movements, the mutation in DCC prevents it from helping,

“nerve cells on one side of the spinal cord to stay on that side as they extend processes up and down the developing spine…. Because the protein is malformed, the body develops neural connections that route one-sided connections to both sides, producing the mirrored activity.”

I don’t have access to Science unfortunately to research the demographics of the particular SNP they discovered… So I can’t tell you of the gene frequencies… But if anyone does have access to the paper, and doesn’t emailing me, I’ll be very grateful. I love these sorts of discoveries where I learn something new and integrate what I’ve learned the past year and half of medical school!

    Srour M, Rivière JB, Pham JM, Dubé MP, Girard S, Morin S, Dion PA, Asselin G, Rochefort D, Hince P, Diab S, Sharafaddinzadeh N, Chouinard S, Théoret H, Charron F, & Rouleau GA (2010). Mutations in DCC cause congenital mirror movements. Science (New York, N.Y.), 328 (5978) PMID: 20431009

April 30, 2010

56 Family Portraits From East Asia

I haven’t bothered to translate this page, but I’ve stumbled across a collection of 56 family portraits from East Asia that I wanted to share with you. The images give us a quick glimpse of all the different cultures and ethnicities that make up the far East, along with the lat/long of where these people are found. Check it out.

Ethnic Mongol

Ethnic Mongol

April 8, 2010

Australopithecus sediba (UW88-50) of Malapa, South Africa

Lee Berger’s son, Matthew, found the ~1.9 million year old hominin remains of female adult and a juvenile male in cave deposits at Malapa, South Africa. The remains have been analyzed and been published in Science today, and so far this finding is the big fossil hominid of 2010. The skull of the juvenile is the cover image for this week’s issue of Science.

Australopithecus sediba on the cover of Science

Australopithecus sediba on the cover of Science

Today’s paleoanthropology new is what was eluded to by a commenter last month. I talked to some colleagues about what the commenter could have been referring to back then, and they told me Berger’s gonna be releasing his findings on UW88-50. I didn’t report on it then because of several reasons, one of which was time constraints but also because I really didn’t have much information on the fossils. There’s a lot more press out today about it and while, I don’t have much time to digest it all, I figured I’ll at least share it with you in case you’ve been living under a rock.

The remains have been given a new species classification, Australopithecus sediba and are probably descendants of Australopithecus africanus. Like every other new fossil hominin species, there’s an array of archaic and modern features. The small teeth, projecting nose, very advanced pelvis, along with the long legs are the more modern features. The archaic features are the long arms and small brain case. What is special about Australopithecus sediba is that the hominin fossil record is pretty sparse around 1.9 million years ago and this fossil helps fill that gap.

Check out the news coverage, BBC, ABC News

    Berger, L., de Ruiter, D., Churchill, S., Schmid, P., Carlson, K., Dirks, P., & Kibii, J. (2010). Australopithecus sediba: A New Species of Homo-Like Australopith from South Africa Science, 328 (5975), 195-204 DOI: 10.1126/science.1184944
    Dirks, P., Kibii, J., Kuhn, B., Steininger, C., Churchill, S., Kramers, J., Pickering, R., Farber, D., Meriaux, A., Herries, A., King, G., & Berger, L. (2010). Geological Setting and Age of Australopithecus sediba from Southern Africa Science, 328 (5975), 205-208 DOI: 10.1126/science.1184950