Are Rapidly Evolving Human Promoter Regions Due To Higher Rates Of Neutral Substitution Or Positive Selection?

Nature Genetics just published a brief correspondence on the evolution of promoter regions in the human genome. The basis of this study relies on the observation that 46% of promoter regions in the human genome have a higher number of nucleotide substitutions than corresponding introns. The authors don't make the distinction that positive selection, relaxed... Continue Reading →

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