Are Rapidly Evolving Human Promoter Regions Due To Higher Rates Of Neutral Substitution Or Positive Selection?

Nature Genetics just published a brief correspondence on the evolution of promoter regions in the human genome. The basis of this study relies on the observation that 46% of promoter regions in the human genome have a higher number of nucleotide substitutions than corresponding introns. The authors don't make the distinction that positive selection, relaxed... Continue Reading →

SLC45A2/MATP & The Genetics Of Human Hair Color

Earlier this year, I wrote a massive summary on the genetics of pigmentation for one of my graduate courses. I wasn't particularly keen on the topic before but it has since grown on me and I'm now a big fan. So to read from Yann, Dienekes, and Razib that one of the key pigmentation genes,... Continue Reading →

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